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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e48680cfc07d520c885e2295a20fee3609c45675386956a003234d29b0ecf551' 
  AND token = 'ejsg0PI6xqeB+3xv6eE5b7s3ZsqPHwiTTpLGCd4Bg/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}