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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e280de07fdf746013554ccb3857d71fc850ad6bc926dab333af87e2836c81060' 
  AND token = 'w0EZE4sFjjfk9PIueej8ozl9+UTHo+Ln0f/mb+gyxq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}