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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '423e86d21f247737dd672bf009a604d161dce5cc4a5c25c8a580d17ccfaac33f' 
  AND token = '6riRrmwmKCtNKJpzFzeJcc+1KC/rruuz/bfer9SU3MA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}