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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ab56b22502473b18df5a0f0d9081d000a2fd98ce522d28d55df1c687557afd' 
  AND token = '/yU2pGuUUrfW+lTzPVpygsNTpg+c4VsoIJl8hAEwH74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}