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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8d1ac4023468092bcea1d969af1c54aa4c9f1a53853d33e09f0c370d6d1ffe2' 
  AND token = 'pyYmv3M2NhSMo2cQFPxsTFZiHN9re6psdNY4OxHyusQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}