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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5002a0398a761b4008cd221273384185af2fcd08f873c69342c8fa123ddf3f3' 
  AND token = 'v9NoWgX+lMZEcykSq2g2KeCdljfUoua9P/HdVpnISBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}