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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43fb364ed0472a0bc9a998bf712e6353b8830a8de8f9598f6aefee1d78b2633e' 
  AND token = 'jq3HUkGl6sPF6Vvng63E4qR2QQrfr8GKjv5U39UJW0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}