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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a7145136d2d6f8a9e252bf989525185e48481de14ac21d6e44394060e3f370f' 
  AND token = 'UMplV7b5W7zAg0kRN0f3KbmZ5xBBauvr2uFR/1s9FwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}