SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd66a5a541a3e8dea9b44154582d74e4ee2dde19344d201122aae960bd39a18e7' 
  AND token = 'vhOPeVzN6v4nuyLazvZf4Zk3R+aCWK+7c24FrfJHSBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}