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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74edb33a21f899abeac5449ff84f7dfcf84b645eb5290965cfd666e005e4c2b5' 
  AND token = 'qyasI4yOJIDmLHXK+xOOA4HTFzFdLcLnj0ZF2P4bOZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}