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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a3fa13de9fd5ba2767f0f6ffbb725f713fff890a061a9a0ba23ef4057ac37dc' 
  AND token = '43skAkEtmQ9rpsgyffwaer22frsvrI082siIzEHjYsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}