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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5080ba4b00fa0ba93b1eb64dc7879d9f23cc76073379ea2b4db5a2786a7a080f' 
  AND token = 'yIQF9kD1H45GbFwIaFImvQpyfCQenG4fpc2AiGWj7aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}