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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ca4304a1e3b2d134f7483d2750c074e08543d0b71e58087f0cd5f8f749c8019' 
  AND token = 'Qiv2ykfFCFhIUYYNMt/TQM4mRVIOUTZAvF1fsF/NBH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}