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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2caf2ca7dfdd3d64a5258b8eadd220bc5d8673dd4123d2bcf8169d321fe454c' 
  AND token = 'uOiYvEx4p3KH30uYuTMTEB8PjeJsZLWoOB4Hpze0+qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}