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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '157074fe8eca4f338f6e48a49f16ce18b21420d382070a4da6b766c2dfabff46' 
  AND token = 'lOxx5c1Jdv8fBpI8FKqKseqmaQvNmcPuK6hdCND4CT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}