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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac81378a03ba663754867b1ce0ad5e719c05f860ba8ef3af8e4ed0cbb045139c' 
  AND token = 'm60mHVgpUJlQ0RGCvzCpZhkCSSHpQoNCxhNgFQkkhv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}