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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218f3ec9b1733a05c60e6fe77188867f6e456aab43405b39d61139fc84b5b7e5' 
  AND token = 'I070KinsP/mC3aCBekLmbCkhOA9fZYkNl3NQ5vvETII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}