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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '112888dafab5daa20d37bc0fa307f537ecb48644189aa8d3f9935f6be67e3556' 
  AND token = 'DZrUl+2Waioi8LMRBSzN7OemEPnFnyy1uq18vALc4P8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}