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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4398a83f1b510df0d1500bf87ccbb45cebe647ea49b4b909a548f1779f011bf5' 
  AND token = 'ds+li3mpjY/BpDeKUa5Xm49uwjeUzzbhgAqrOsuysfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}