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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21f19aa08795389af9fdfbc4fc128ed65d93ff280b3343e05f169e492242ce9b' 
  AND token = 'r1QMJ75AYZ6xehJLO6veMUv3aIBXJ/8Qme/2H4MRx/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}