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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e49ff6c35183bb42fe886921cdde05d7d15a9c02acbc47a97de5f35e8b28e4b' 
  AND token = '42x+lcQHMIQ4iFkrFVSzw1LhL4oYVBN92oCTvPUMyWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}