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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2d8b6dc3b1654a150f6de400697496ca261a7129fe92eb1308627a27cf7722' 
  AND token = '8OPN1KX/V33V5gzoOPGPVpra74FVmna3mvID8acUa5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}