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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd14ad428091a05265f8c0edf94f65b2f81c1f7445f7a1011a625f5b3621e3412' 
  AND token = 'iCAHAY2iRF6bglNzesXjZl64YwuT3cMxsh1BpOpG/bQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}