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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab22583bf4349a9be40fc694a56569f9656b0163a6711d410c59e402765ca6e6' 
  AND token = 'qq4JasMh8g4WyxE2Mp6SOYsx1AOlVrxy39CFYqVrkPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}