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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '301e9fc9daa347a4f0cdb829f3e5a56823a75baf38ca692cef0384a5b35a5eb8' 
  AND token = '8N5eHZj1m4pWiR+5qZ0xqSZvPW5EkXZ3onir6/BtUp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}