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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f452c1a900519c2c37aaa2f3444e9cd63d9cedc4b23d1a0e78ce5844bea47a' 
  AND token = 'OsGOo7jJUdHIO4RVe/Vgie6DnnwVkHjIbn/A16Ynaj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}