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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62253c7bf89a8e7a8b280b6eb7b212ddffbe4642a9d59feea8948494e5d5cc55' 
  AND token = 'eoDUWjUZr1NeRduJHFhLrkSTxpdd4acM6+UQlhT06ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}