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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b5c24324854f45bdb1d52464ade6b579988b5450323c04e47c7b42d59881985' 
  AND token = '4wYkFNUPva3kCgma92fP03buZNaleSBO9dlyY2YBk0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}