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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73b601887b38e03549de38d1b3032736a30e92458d895d906c0f9496e95e4789' 
  AND token = 'KjDU3r+IipzHWoE1ywhqTbV3DyF3qKdSoq1CUm21Ejc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}