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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42166d5f3eee94a9a93e4461b5131222915505e954e3e7c62792ca654b6c9233' 
  AND token = 'Qge+nxhP0k0+luhSFybA7s1RHfPBRQCru0X/OTlZ0PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}