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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b86b47bf49a07c54dee4cf4085eeb403d1cce7304b2a424ff7fa75e52ec5b6c' 
  AND token = 'yQ3q8L2PHyTwXn4PA9hTbS/b5uUCN/Pq0SClR5Q6fQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}