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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01cb25a9f69f933e9d00cd765057ce31ecb94a6268ee2b439576b7feeff635a2' 
  AND token = 'gPv1MMYq7EXiEf4Fao7rcFgHi53WNiDQGJ0aBNOYvX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}