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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a85dd127842f08f767aea5ea4ac5fb5898fd50fd376470fc944d19b73f8455' 
  AND token = 'x9ifDDFiMh5hzWqzb7Hv/pRulMiUAgh08dvBJS0taJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}