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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c76548caff9f8550f01d7e4f32fed4fe1ceab3096cfd241e15f34c31188ca4' 
  AND token = 'MhVP8yJnYR2ScSTDR8lEWsI9tvA+mPGwuXXBQc1EWhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}