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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d0d4c09bce7c92ddb2680468a3b30890b6fe021a79dc86fba1647de0f10eedb' 
  AND token = 'LK2acfRsYopI0zFvZ3wEr+edo+uql1pI3VKql8Ns/8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}