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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '701284c4ca91d359728f8e2a3e1f1a2e60826702da21781d60926907dd4cfe04' 
  AND token = '+JDe/MES/SZ7bk1GNfrxGokEN7+VHL7yq/w4KaMgY70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}