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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0d5c6cc516ee0610591be4ea0e68e26fb8ea4d2239ff60fba2b89875f4166d2' 
  AND token = 'MZA1wKTzQ/Boy0tlXZg3lFYVN3LpjW36DBd2RqqSbc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}