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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8d66fabb1deb57b71fef04ef69aa239f79350b7e778f000db0db553ca20d5b3' 
  AND token = 'u+rwJas2LXatTAVruvQGXiNi9t/R62dZPKLgijCfHF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}