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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '395e982c921709809f0395c9aee472fe3c40673dfb45002032dd4c0f707af16a' 
  AND token = 'YHm9KvRhiBzYMby9rYIfVNQCN+YqPh2CFdi/0D7Nywk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}