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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a72add647794b60d72cc277fb4979f4d764f3e9ff6435e2732b693b2de2fc76' 
  AND token = 'JAcNZ7EH9ThmS/i4win3fOYqopP0kpNUe/4yQui1E7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}