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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180b28619bf255ca559ee2353d00ac60a48a03fdfe28710c6dc2362b94345ea2' 
  AND token = 'XBG2ip+R4WGq86uX5PNQwIWGAxUxlUh7EXbSW9StK6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}