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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbb173753770ae1d0d993d3653b1967c48409e34da836d54346120fefebfbd90' 
  AND token = 'VJ6Taej28zFQRENo1o/LD8DnDFBAP2urwtMTJ6EeSZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}