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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c9b981d71c383ae996df1929997e3863aa04fd8c585740b0a4e0323c4a05b4' 
  AND token = '4rIE/j9moFHN+7e4DsnE/aIvFbNp2xqAr1gP9utQ+58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}