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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def0357e0401aa04657d416241b21b4e0d259cc6871527f9ef1861411af7a258' 
  AND token = 'Rb0v2VkoZnA+8kjtRmPJMkyCan0xb8UVz14kJ//Cyds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}