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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e5bfefe13511298682070107c3a5f584232a91e40c169619a9bbc3870d7e10' 
  AND token = 'F1gciwD2pW2LxrIZyLSnuLAiapQPZK6vuASnMUr5L0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}