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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89e7a1e1ea824cde7e462a88a653b22d9ec63e99227919a9a1d240d7a572dac3' 
  AND token = 'AqvZfU69FKD7oDH+D3rrpTFIQ0MLKnkR9EQDN6eYhRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}