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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7db999b43302c9072ac919a2c9f0e9008d7281c0d59206fb073d2070173daaa' 
  AND token = 'JyuyN6d6hmMEjohRIcZ3JJcCk+qAaQQ7jo+1C/3MOs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}