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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20fb079ba0c28aab08ef21d7c1186197e7fe8c46281f614de15539f89a9b94a7' 
  AND token = 'hdhUjyQXK+INiLe8UFmKThqkW5nTOU+xE31W70qGsk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}