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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c749d2cb1874b692b156c93a8002e46182c9c98a29e5a3d5f372128c426f2f12' 
  AND token = 'Hfn9eYyUZBkwQLB8R2zqi+Iwme9HpAWPeBM6JumN1ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}