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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90e70c2b89dcd2d468c3209ff024c754845a18ac68497cdd5315bdad155a7ed4' 
  AND token = 'ZZZ2Pd8IF6s3TQLxa167L/QRMI2S/mAv+4dtrTO6LvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}